Nebenwirkungen

Posted on by admin

In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug. Developing drugs is a complicated process, because no two people are exactly the same, so even drugs that have virtually no side effects, might be difficult for some people. Also, it is difficult to make a drug that targets one part of the body but that does not affect other parts,[1] the fact that increases the risk of side effects in the untargeted parts.

You can use this site to report an adverse event or product quality complaint. You can also ask a medical information inquiry. 5,376 Followers, 733 Following, 420 Posts - See Instagram photos and videos from Stephanie Kasper (@papierschorsch).

Occasionally, drugs are prescribed or procedures performed specifically for their side effects; in that case, said side effect ceases to be a side effect and is now an intended effect. For instance, X-rays were historically (and are currently) used as an imaging technique; the discovery of their oncolytic capability led to their employ in radiotherapy (ablation of malignanttumours).

Frequency of side effects[edit]

The probability or chance of experiencing side effects are characterised as : [2][3]

  • Very common, ≥ 1⁄10
  • Common (frequent), 1⁄100 to 1⁄10
  • Uncommon (infrequent), 1⁄1000 to 1⁄100
  • Rare, 1⁄10000 to 1⁄1000
  • Very rare, < 1⁄10000

Nebenwirkungen Novalgin

Examples of therapeutic side effects[edit]

Possible side effects of nicotine.[4]
  • Bevacizumab (Avastin), used to slow the growth of blood vessels, has been used against dry age-related macular degeneration, as well as macular edema from diseases such as diabetic retinopathy and central retinal vein occlusion.[5]
  • Buprenorphine has been shown experimentally (1982–1995) to be effective against severe, refractory depression.[6][7]
  • Bupropion (Wellbutrin), an anti-depressant, is also used as a smoking cessation aid; this indication was later approved, and the name of the smoking cessation product is Zyban. In Ontario, Canada, smoking cessation drugs are not covered by provincial drug plans; elsewhere, Zyban is priced higher than Wellbutrin, despite being the same drug. Therefore, some physicians prescribe Wellbutrin for both indications.[citation needed]
  • Carbamazepine is an approved treatment for bipolar disorder and epileptic seizures, but it has side effects useful in treating attention-deficit hyperactivity disorder (ADHD), schizophrenia, phantom limb syndrome, paroxysmal extreme pain disorder, neuromyotonia, and post-traumatic stress disorder.[8]
  • Dexamethasone and betamethasone in premature labor, to enhance pulmonary maturation of the fetus.[9]
  • Doxepin has been used to treat angiodema and severe allergic reactions due to its strong antihistamine properties.[10]
  • Gabapentin, approved for treatment of seizures and postherpetic neuralgia in adults, has side-effects which are useful in treating bipolar disorder1, essential tremor, hot flashes, migraine prophylaxis, neuropathic pain syndromes, phantom limb syndrome, and restless leg syndrome.[11]
  • Hydroxyzine, an antihistamine, is also used as an anxiolytic.[citation needed]
  • Magnesium sulfate in obstetrics for premature labor and preeclampsia.[9]
  • Methotrexate (MTX), approved for the treatment of choriocarcinoma, is frequently used for the medical treatment of an unruptured ectopic pregnancy.[12]
  • The SSRI medication sertraline is approved as an antidepressant but delays conjugal climax in men, and thus may be supplied to those in which climax is premature.[13]
  • Sildenafil was originally intended for pulmonary hypertension; subsequently, it was discovered that it also produces erections, for which it was later marketed.[citation needed]
  • Terazosin, an α1-adrenergic antagonist approved to treat benign prostatic hyperplasia (enlarged prostate) and hypertension, is (one of several drugs) used off-label to treat drug induced diaphoresis and hyperhidrosis (excessive sweating).[14][15]

Examples of undesirable/unwanted side effects[edit]

  • Echinacea – more than 20 different types of reactions have been reported, including asthma attacks, loss of pregnancy, hives, swelling, aching muscles and gastrointestinal upsets.[16]
  • Feverfew – pregnant women should avoid using this herb, as it can trigger uterine contractions which could lead to premature labour or miscarriage.[17]
  • Asteraceae plants – which include feverfew, echinacea, dandelion and chamomile. Side effects include allergic dermatitis and hay fever.[citation needed]

See also[edit]

  • Pharmacogenetics: the use of genetic information to determine which type of drugs will work best for a patient

References[edit]

  1. ^'Why do side effects occur? Guides HIV i-Base'. i-base.info.
  2. ^'Common and Rare Side Effects for misoprostol oral'.
  3. ^'Archived copy'(PDF). Archived(PDF) from the original on 2016-03-04. Retrieved 2016-04-29.CS1 maint: archived copy as title (link)
  4. ^Detailed reference list is located on a separate image page.
  5. ^Boseley, Sarah (2006-06-17). 'Drugs firm blocks cheap blindness cure'. The Guardian. London. Retrieved 2010-05-20.
  6. ^Gracer, Richard (February 2007). 'The Buprenorphine Effect on Depression'(PDF). naabt.org. National Alliance of Advocates for Buprenorphine Treatment. Retrieved 19 September 2015.
  7. ^Bodkin, JA; Zornberg, GL; Lukas, SE; Cole, JO (1995). 'Buprenorphine Treatment of Refractory Depression'. Journal of Clinical Psychopharmacology. 15 (1): 49–57. doi:10.1097/00004714-199502000-00008. PMID7714228.
  8. ^Mood Stabilizers for Bipolar Disorder (Manic Depressive)Archived 2011-11-13 at the Wayback Machine. Leeheymd.com (2003-08-01). Retrieved on 2011-08-17.
  9. ^ abWing, DA; Powers, B; Hickok, D (2010). 'U.S. Food and Drug Administration Drug Approval: Slow Advances in Obstetric Care in the United States'. Obstetrics & Gynecology. 115 (4): 825–33. doi:10.1097/AOG.0b013e3181d53843. PMID20308845.
  10. ^Shen, WW; Mahadevan, J; Hofstatter, L; Sata, LS (July 1983). 'Doxepin as a potent H2 and H2 antihistamine for epigastric distress'. Am J Psychiatry. 140 (7): 957–8. doi:10.1176/ajp.140.7.957. PMID6859336. Archived from the original on 2011-09-04.
  11. ^Off-label Use of GabapentinArchived 2007-08-09 at the Wayback Machine, Idaho Drug Utilization Review, educational leaflet, 2004.
  12. ^'Pregnancy'. drugs.nmihi.com. (New Medical Information and Health Information). Archived from the original on 11 October 2008.
  13. ^Deem, Samuel G. 'Premature Ejaculation'. Emedicine.com. Archived from the original on 2008-12-01. Retrieved 2011-08-17.
  14. ^Gelenberg, Alan J.; et al. (2010). Practice guideline for the treatment of patients with major depressive disorder(PDF). American Psychiatric Association.
  15. ^Cheshire, William P.; Fealey, Robert D. (2008). 'Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management'(PDF). Drug Safety. 31 (2): 109–126. doi:10.2165/00002018-200831020-00002. ISSN0114-5916. PMID18217788.
  16. ^'Filagra Vs Fildena'. Filagra100mg.com. 23 February 2017. Archived from the original on 3 July 2017.
  17. ^Wells, Rebecca Erwin; Turner, Dana P.; Lee, Michelle; Bishop, Laura; Strauss, Lauren (2016-04-01). 'Managing Migraine During Pregnancy and Lactation'. Current Neurology and Neuroscience Reports. 16 (4): 40. doi:10.1007/s11910-016-0634-9. ISSN1528-4042. PMID27002079.

External links[edit]

Retrieved from 'https://en.wikipedia.org/w/index.php?title=Side_effect&oldid=1000975790'

Cipralex Nebenwirkungen

Generic Name: Rasagiline (ra SA ji leen)
Brand Name: Azilect

Medically reviewed by Drugs.com. Last updated on Aug 19, 2020.

Uses of Rasagiline:

  • It is used to treat Parkinson's disease.
Nebenwirkungen

What do I need to tell my doctor BEFORE I take Rasagiline?

  • If you have an allergy to rasagiline or any other part of rasagiline.
  • If you are allergic to rasagiline; any part of rasagiline; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have liver disease.
  • If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with rasagiline, like certain drugs that are used for cough or cold, depression or other mood problems, or pain. There are many drugs that must not be taken with rasagiline.
  • If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline in the last 14 days. Taking rasagiline within 14 days of those drugs can cause very bad high blood pressure.
  • If you have taken fluoxetine within the last 5 weeks. Do not start rasagiline if you have taken fluoxetine within the last 5 weeks.

This is not a list of all drugs or health problems that interact with rasagiline.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take rasagiline with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Rasagiline?

  • Tell all of your health care providers that you take rasagiline. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how rasagiline affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
  • Do not stop taking rasagiline all of a sudden without calling your doctor. You may have a greater risk of side effects. If you need to stop rasagiline, you will want to slowly stop it as ordered by your doctor.
  • Some foods and drinks, like cheese and red wine, may cause sudden, severe high blood pressure when you are taking rasagiline. This effect can be deadly. Talk with your doctor about your risk for this effect. Get a list of foods and drinks to avoid. Avoid these foods and drinks for as long as your doctor has told you after rasagiline is stopped.
  • Some people have fallen asleep during activities like driving, eating, or talking. Some people did not feel sleepy and felt alert right before falling asleep. This has happened up to 1 year after rasagiline was started. If you fall asleep during activities, do not drive or do other tasks or actions that call for you to be alert while you take rasagiline. Call your doctor right away if this happens or you feel very sleepy.
  • High or low blood pressure may happen with rasagiline. Have your blood pressure checked as you have been told by your doctor.
  • If you are taking rasagiline and have high blood pressure, talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.
  • The chance of a type of skin cancer called melanoma may be raised in people with Parkinson's disease. It is not known if rasagiline may also raise the chance. Have skin exams while you take rasagiline. Talk with your doctor.
  • Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using rasagiline while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Rasagiline) best taken?

Use rasagiline as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food.
  • Keep taking rasagiline as you have been told by your doctor or other health care provider, even if you feel well.

What do I do if I miss a dose?

  • Skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
Rasagiline dosage(more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
  • Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking.
  • Shakiness, trouble moving around, or stiffness.
  • Strong urges that are hard to control (such as eating, gambling, sex, or spending money).
  • A skin lump or growth.
  • Change in color or size of a mole.
  • Hallucinations (seeing or hearing things that are not there).
  • Change in the way you act.
  • Mood changes.
  • Shortness of breath.
  • A burning, numbness, or tingling feeling that is not normal.
  • Swelling in the arms or legs.
  • A severe and sometimes deadly problem called serotonin syndrome may happen if you take rasagiline with certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; severe diarrhea, upset stomach, or throwing up; or severe headache.

What are some other side effects of Rasagiline?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Flu-like signs.
  • Headache.
  • Upset stomach or throwing up.
  • Constipation.
  • Diarrhea.
  • Dizziness.
  • Feeling sleepy.
  • Dry mouth.
  • Not hungry.
  • Belly pain.
  • Weight loss.
  • Strange or odd dreams.
  • Joint pain.
  • Bruising.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Rasagiline?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Ramipril nebenwirkungen

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about rasagiline, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about rasagiline

  • During Pregnancy or Breastfeeding

Consumer resources

Other brands:Azilect

Professional resources

Related treatment guides